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Antidepressant-like Effects of LPM580153, A Novel Potent Triple Reuptake Inhibitor

The purpose of this study was to characterize a novel compound, 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl) ethyl] phenyl 3-nitrophenyl ether, designated LPM580153. We used several well-validated animal models of depression to assess the antidepressant-like activity of LPM580153, followed by a neur...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Zhang, Fangxi, Shao, Jing, Tian, Jingwei, Zhong, Yan, Ye, Liang, Meng, Xiangjing, Liu, Qiaofeng, Wang, Hongbo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823741/
https://ncbi.nlm.nih.gov/pubmed/27052887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24233
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