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Lisdexamfetamine Dimesylate: Prodrug Delivery, Amphetamine Exposure and Duration of Efficacy

Lisdexamfetamine dimesylate (LDX) is a long-acting d-amphetamine prodrug used to treat attention-deficit/hyperactivity disorder (ADHD) in children, adolescents and adults. LDX is hydrolysed in the blood to yield d-amphetamine, and the pharmacokinetic profile of d-amphetamine following oral administr...

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Detalles Bibliográficos
Publicado en:Clin Drug Investig
Main Authors: Ermer, James C., Pennick, Michael, Frick, Glen
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823324/
https://ncbi.nlm.nih.gov/pubmed/27021968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-015-0354-y
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