The TGF-β/SMAD pathway is an important mechanism for NK cell immune evasion in childhood B acute lymphoblastic leukemia

Natural killer (NK) cells are key components of the innate immune system, providing potent antitumor immunity. Here, we show that the TGF-β/SMAD signaling pathway is an important mechanism for NK cell immune evasion in childhood B-acute lymphoblastic leukemia (ALL). We characterized NK cells in 50 c...

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Vydáno v:Leukemia
Hlavní autoři: Rouce, Rayne H., Shaim, Hila, Sekine, Takuya, Weber, Gerrit, Ballard, Brandon, Ku, Stephanie, Barese, Cecilia, Murali, Vineeth, Wu, Meng-Fen, Liu, Hao, Shpall, Elizabeth J., Bollard, Catherine M., Rabin, Karen R., Rezvani, Katayoun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823160/
https://ncbi.nlm.nih.gov/pubmed/26621337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.327
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