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Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells

Cancer stem cells (CSCs) appear to explain many aspects of the neoplastic evolution of tumors and likely account for enhanced therapeutic resistance following treatment. Dysregulated Notch signaling, which affects CSCs plays an important role in pancreatic cancer progression. We have determined the...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Ponnurangam, Sivapriya, Dandawate, Prasad R., Dhar, Animesh, Tawfik, Ossama W., Parab, Rajashri R., Mishra, Prabhu Dutt, Ranadive, Prafull, Sharma, Rajiv, Mahajan, Girish, Umar, Shahid, Weir, Scott J., Sugumar, Aravind, Jensen, Roy A., Padhye, Subhash B., Balakrishnan, Arun, Anant, Shrikant, Subramaniam, Dharmalingam
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823101/
https://ncbi.nlm.nih.gov/pubmed/26673007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6560
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