Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells

Cancer stem cells (CSCs) appear to explain many aspects of the neoplastic evolution of tumors and likely account for enhanced therapeutic resistance following treatment. Dysregulated Notch signaling, which affects CSCs plays an important role in pancreatic cancer progression. We have determined the...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ponnurangam, Sivapriya, Dandawate, Prasad R., Dhar, Animesh, Tawfik, Ossama W., Parab, Rajashri R., Mishra, Prabhu Dutt, Ranadive, Prafull, Sharma, Rajiv, Mahajan, Girish, Umar, Shahid, Weir, Scott J., Sugumar, Aravind, Jensen, Roy A., Padhye, Subhash B., Balakrishnan, Arun, Anant, Shrikant, Subramaniam, Dharmalingam
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823101/
https://ncbi.nlm.nih.gov/pubmed/26673007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6560
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