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Tumor-associated fibroblast-conditioned medium induces CDDP resistance in HNSCC cells

OBJECTIVE: EMT (epithelial to mesenchymal transition) contributes to tumor progression and metastasis. We aimed to investigate the effects of EMT on CDDP resistance in HNSCC (head and neck squamous cell carcinoma)-cells. METHODS: EMT was induced using conditioned medium from a tumor cell/fibroblast...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Steinbichler, Teresa Bernadette, Metzler, Veronika, Pritz, Christian, Riechelmann, Herbert, Dudas, Jozsef
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823051/
https://ncbi.nlm.nih.gov/pubmed/26497215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6210
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