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Targeting Survivin Enhances Chemosensitivity in Retinoblastoma Cells and Orthotopic Tumors

Treatments for retinoblastoma (Rb) vary depending on the size and location of the intraocular lesions and include chemotherapy and radiation therapy. We examined whether agents used to treat Rb induce a pro-survival phenotype associated with increased expression of survivin, a member of the inhibito...

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Publicat a:PLoS One
Autors principals: Ferrario, Angela, Luna, Marian, Rucker, Natalie, Wong, Sam, Lederman, Ariel, Kim, Jonathan, Gomer, Charles
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822873/
https://ncbi.nlm.nih.gov/pubmed/27050416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153011
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