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Targeting Survivin Enhances Chemosensitivity in Retinoblastoma Cells and Orthotopic Tumors

Treatments for retinoblastoma (Rb) vary depending on the size and location of the intraocular lesions and include chemotherapy and radiation therapy. We examined whether agents used to treat Rb induce a pro-survival phenotype associated with increased expression of survivin, a member of the inhibito...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Ferrario, Angela, Luna, Marian, Rucker, Natalie, Wong, Sam, Lederman, Ariel, Kim, Jonathan, Gomer, Charles
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822873/
https://ncbi.nlm.nih.gov/pubmed/27050416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153011
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