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Maximally asymmetric transbilayer distribution of anionic lipids alters the structure and interaction with lipids of an amyloidogenic protein dimer bound to the membrane surface

We used molecular dynamics simulations to explore the effects of asymmetric transbilayer distribution of anionic phosphatidylserine (PS) lipids on the structure of a protein on the membrane surface and subsequent protein–lipid interactions. Our simulation systems consisted of an amyloidogenic, beta-...

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Vydáno v:Chem Phys Lipids
Hlavní autoři: Cheng, Sara Y., Chou, George, Buie, Creighton, Vaughn, Mark W., Compton, Campbell, Cheng, Kwan H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822834/
https://ncbi.nlm.nih.gov/pubmed/26827904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2016.01.002
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