Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication

DNA Polymerases generate pyrophosphate every time they catalyze a step of DNA elongation. This elongation reaction is generally believed as thermodynamically favoured by the hydrolysis of pyrophosphate, catalyzed by inorganic pyrophosphatases. However, the specific action of inorganic pyrophosphatas...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lapenta, Fabio, Montón Silva, Alejandro, Brandimarti, Renato, Lanzi, Massimiliano, Gratani, Fabio Lino, Vellosillo Gonzalez, Perceval, Perticarari, Sofia, Hochkoeppler, Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822814/
https://ncbi.nlm.nih.gov/pubmed/27050298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152915
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