LSD1 modulates stress-evoked transcription of immediate early genes and emotional behavior

Behavioral changes in response to stressful stimuli can be controlled via adaptive epigenetic changes in neuronal gene expression. Here we indicate a role for the transcriptional corepressor Lysine-Specific Demethylase 1 (LSD1) and its dominant-negative splicing isoform neuroLSD1, in the modulation...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Rusconi, Francesco, Grillo, Barbara, Ponzoni, Luisa, Bassani, Silvia, Toffolo, Emanuela, Paganini, Leda, Mallei, Alessandra, Braida, Daniela, Passafaro, Maria, Popoli, Maurizio, Sala, Mariaelvina, Battaglioli, Elena
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822633/
https://ncbi.nlm.nih.gov/pubmed/26976584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511974113
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