Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma

BACKGROUND: Glaucoma is a complex, multifactorial disease characterised by the loss of retinal ganglion cells and their axons leading to a decrease in visual function. The earliest events that damage retinal ganglion cells in glaucoma are currently unknown. Retinal ganglion cell death appears to be...

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Publicat a:Mol Neurodegener
Autors principals: Williams, Pete A., Tribble, James R., Pepper, Keating W., Cross, Stephen D., Morgan, B Paul, Morgan, James E., John, Simon W. M., Howell, Gareth R.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822272/
https://ncbi.nlm.nih.gov/pubmed/27048300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0091-6
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