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Learning defects in Drosophila growth restricted chico mutants are caused by attenuated adenylyl cyclase activity

BACKGROUND: Reduced insulin/insulin-like growth factor signaling (IIS) is a major cause of symmetrical intrauterine growth retardation (IUGR), an impairment in cell proliferation during prenatal development that results in global growth defects and mental retardation. In Drosophila, chico encodes th...

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Veröffentlicht in:Mol Brain
Hauptverfasser: Naganos, Shintaro, Ueno, Kohei, Horiuchi, Junjiro, Saitoe, Minoru
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822261/
https://ncbi.nlm.nih.gov/pubmed/27048332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0217-3
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