Proximity assays for sensitive quantification of proteins

Proximity assays are immunohistochemical tools that utilise two or more DNA-tagged aptamers or antibodies binding in close proximity to the same protein or protein complex. Amplification by PCR or isothermal methods and hybridisation of a labelled probe to its DNA target generates a signal that enab...

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Detalles Bibliográficos
Publicado en:Biomol Detect Quantif
Autores principales: Greenwood, Christina, Ruff, David, Kirvell, Sara, Johnson, Gemma, Dhillon, Harvinder S., Bustin, Stephen A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822221/
https://ncbi.nlm.nih.gov/pubmed/27077033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bdq.2015.04.002
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