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Three-dimensional direct measurement of cardiomyocyte volume, nuclearity, and ploidy in thick histological sections

Quantitative assessment of myocardial development and disease requires accurate measurement of cardiomyocyte volume, nuclearity (nuclei per cell), and ploidy (genome copies per cell). Current methods require enzymatically isolating cells, which excludes the use of archived tissue, or serial sectioni...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bensley, Jonathan Guy, De Matteo, Robert, Harding, Richard, Black, Mary Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822151/
https://ncbi.nlm.nih.gov/pubmed/27048757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23756
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