Serial interactome capture of the human cell nucleus

Novel RNA-guided cellular functions are paralleled by an increasing number of RNA-binding proteins (RBPs). Here we present ‘serial RNA interactome capture' (serIC), a multiple purification procedure of ultraviolet-crosslinked poly(A)–RNA–protein complexes that enables global RBP detection with...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Conrad, Thomas, Albrecht, Anne-Susann, de Melo Costa, Veronica Rodrigues, Sauer, Sascha, Meierhofer, David, Ørom, Ulf Andersson
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822031/
https://ncbi.nlm.nih.gov/pubmed/27040163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11212
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