Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

Plasmodium knowlesi is a zoonotic parasite transmitted from macaques causing malaria in humans in Southeast Asia. Plasmodium parasites bind to red blood cell (RBC) surface receptors, many of which are sialylated. While macaques synthesize the sialic acid variant N-glycolylneuraminic acid (Neu5Gc), h...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Dankwa, Selasi, Lim, Caeul, Bei, Amy K., Jiang, Rays H. Y., Abshire, James R., Patel, Saurabh D., Goldberg, Jonathan M., Moreno, Yovany, Kono, Maya, Niles, Jacquin C., Duraisingh, Manoj T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822025/
https://ncbi.nlm.nih.gov/pubmed/27041489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11187
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