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Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo

Neutrophils are terminally differentiated cells with limited transcriptional activity. The biological function of their gene expression changes is poorly understood. CARD9 regulates transcription during antifungal immunity but its role in sterile inflammation is unclear. Here we show that neutrophil...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Németh, Tamás, Futosi, Krisztina, Sitaru, Cassian, Ruland, Jürgen, Mócsai, Attila
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821996/
https://ncbi.nlm.nih.gov/pubmed/27032818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11004
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