Effects of Chronic Dopamine D2R Agonist Treatment and Polysialic Acid Depletion on Dendritic Spine Density and Excitatory Neurotransmission in the mPFC of Adult Rats

Dopamine D2 receptors (D2R) in the medial prefrontal cortex (mPFC) are key players in the etiology and therapeutics of schizophrenia. The overactivation of these receptors contributes to mPFC dysfunction. Chronic treatment with D2R agonists modifies the expression of molecules implicated in neuronal...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: Castillo-Gómez, Esther, Varea, Emilio, Blasco-Ibáñez, José Miguel, Crespo, Carlos, Nacher, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821975/
https://ncbi.nlm.nih.gov/pubmed/27110404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1615363
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