Effects of Chronic Dopamine D2R Agonist Treatment and Polysialic Acid Depletion on Dendritic Spine Density and Excitatory Neurotransmission in the mPFC of Adult Rats

Dopamine D2 receptors (D2R) in the medial prefrontal cortex (mPFC) are key players in the etiology and therapeutics of schizophrenia. The overactivation of these receptors contributes to mPFC dysfunction. Chronic treatment with D2R agonists modifies the expression of molecules implicated in neuronal...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neural Plast
Main Authors: Castillo-Gómez, Esther, Varea, Emilio, Blasco-Ibáñez, José Miguel, Crespo, Carlos, Nacher, Juan
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821975/
https://ncbi.nlm.nih.gov/pubmed/27110404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1615363
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