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Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension

To maintain tissue integrity during epithelial morphogenesis, adherens junctions (AJs) must resist the mechanical stresses exerted by dynamic tissue movements. Junctional stability is dependent on actomyosin contractility within the actin ring. Here we describe a novel function for the axon guidance...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lee, Natalie K., Fok, Ka Wai, White, Amanda, Wilson, Nicole H., O'Leary, Conor J., Cox, Hayley L., Michael, Magdalene, Yap, Alpha S., Cooper, Helen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821876/
https://ncbi.nlm.nih.gov/pubmed/27029596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11082
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