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HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans

Apoptosis is a prominent metazoan cell death form. Yet, mutations in apoptosis regulators cause only minor defects in vertebrate development, suggesting that another developmental cell death mechanism exists. While some non-apoptotic programs have been molecularly characterized, none appear to contr...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kinet, Maxime J, Malin, Jennifer A, Abraham, Mary C, Blum, Elyse S, Silverman, Melanie R, Lu, Yun, Shaham, Shai
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821803/
https://ncbi.nlm.nih.gov/pubmed/26952214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12821
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