Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID)

Homocysteine is produced physiologically in all cells, and is present in plasma of healthy individuals (plasma [HCy]: 3–10µM). While rare genetic mutations (CBS, MTHFR) cause severe hyperhomocysteinemia ([HCy]: 100–200µM), mild-moderate hyperhomocysteinemia ([HCy]: 10–100µM) is common in older peopl...

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Pubblicato in:Biochim Biophys Acta
Autori principali: Hainsworth, Atticus H, Yeo, Natalie E, Weekman, Erica M, Wilcock, Donna M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821788/
https://ncbi.nlm.nih.gov/pubmed/26689889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.11.015
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