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Multi-perspective smFRET reveals rate-determining late intermediates of ribosomal translocation

Directional translocation of the ribosome through the messenger RNA open reading frame is a critical determinant of translational fidelity. This process entails a complex interplay of large-scale conformational changes within the actively translating particle, which together coordinate the movement...

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Detalles Bibliográficos
Publicado en:Nat Struct Mol Biol
Autores principales: Wasserman, Michael R., Alejo, Jose L., Altman, Roger B., Blanchard, Scott C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821728/
https://ncbi.nlm.nih.gov/pubmed/26926435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3177
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