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A Hidden Markov Model approach to analyze longitudinal ternary outcomes when some observed states are possibly misclassified

Understanding the dynamic disease process is vital in early detection, diagnosis, and measuring progression. Continuous-time Markov chain (CTMC) methods have been used to estimate state change intensities but challenges arise when stages are potentially misclassified. We present an analytical likeli...

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Bibliographic Details
Published in:Stat Med
Main Authors: Benoit, Julia S., Chan, Wenyaw, Luo, Sheng, Yeh, Hung-Wen, Doody, Rachelle
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821697/
https://ncbi.nlm.nih.gov/pubmed/26782946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6861
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