Arid5a regulates naive CD4(+) T cell fate through selective stabilization of Stat3 mRNA

Balance in signal transducer and activator of transcription (STAT) activation is a key factor in regulating the fate of naive CD4(+) T cells. Here, we demonstrate that AT-rich interactive domain-containing protein 5a (Arid5a) in T cells directs naive CD4(+) T cells to differentiate into inflammatory...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Masuda, Kazuya, Ripley, Barry, Nyati, Kishan Kumar, Dubey, Praveen Kumar, Zaman, Mohammad Mahabub-Uz, Hanieh, Hamza, Higa, Mitsuru, Yamashita, Kazuo, Standley, Daron M., Mashima, Tsukasa, Katahira, Masato, Okamoto, Toru, Matsuura, Yoshiharu, Takeuchi, Osamu, Kishimoto, Tadamitsu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821647/
https://ncbi.nlm.nih.gov/pubmed/27022145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151289
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