Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma

During a survey of clinical rectal prolapse (RP) cases in the mouse population at MIT animal research facilities, a high incidence of RP in the lamellipodin knock-out strain, C57BL/6-Raph1(tm1Fbg) (Lpd(-/-)) was documented. Upon further investigation, the Lpd(-/-) colony was found to be infected wit...

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Udgivet i:PLoS One
Main Authors: Miller, Cassandra L., Muthupalani, Sureshkumar, Shen, Zeli, Drees, Frauke, Ge, Zhongming, Feng, Yan, Chen, Xiaowei, Gong, Guanyu, Nagar, Karan K., Wang, Timothy C., Gertler, Frank B., Fox, James G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821566/
https://ncbi.nlm.nih.gov/pubmed/27045955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152940
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