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A Serotonergic System in Veins: Serotonin Transporter-Independent Uptake

We hypothesized that the 5-hydroxytryptamine (5-HT; serotonin) system is present and functional in veins. In vena cava (VC), the presence of the 5-HT synthesis rate-limiting enzyme tryptophan hydroxylase-1 mRNA and accumulation of the 5-HT synthesis intermediate 5-hydroxytryptophan after incubation...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Principais autores: Linder, A. Elizabeth, Ni, Wei, Szasz, Theodora, Burnett, Robert, Diaz, Jessica, Geddes, Timothy J., Kuhn, Donald M., Watts, Stephanie W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821505/
https://ncbi.nlm.nih.gov/pubmed/18322152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.135699
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