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LPA-mediated Migration of Ovarian Cancer Cells Involves Translocalization of Gα(i2) to Invadopodia and Association with Src and β-pix
Lysophosphatidic acid (LPA) plays a critical role in the migration and invasion of ovarian cancer cells. However, the downstream spatiotemporal signaling events involving specific G protein(s) underlying this process are largely unknown. In this report, we demonstrate that LPA signaling causes the t...
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Publicado no: | Cancer Lett |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821470/ https://ncbi.nlm.nih.gov/pubmed/25451317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.030 |
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