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LPA-mediated Migration of Ovarian Cancer Cells Involves Translocalization of Gα(i2) to Invadopodia and Association with Src and β-pix

Lysophosphatidic acid (LPA) plays a critical role in the migration and invasion of ovarian cancer cells. However, the downstream spatiotemporal signaling events involving specific G protein(s) underlying this process are largely unknown. In this report, we demonstrate that LPA signaling causes the t...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Ward, Jeremy D., Ha, Ji Hee, Jayaraman, Muralidharan, Dhanasekaran, Danny N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821470/
https://ncbi.nlm.nih.gov/pubmed/25451317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.030
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