ABCB5-targeted chemoresistance reversal inhibits Merkel cell carcinoma growth

Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer with profound but poorly understood resistance to chemotherapy, which poses a significant barrier to clinical MCC treatment. Here we show that ATP–binding cassette member B5 (ABCB5) confers resistance to standard-of-care M...

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Библиографические подробности
Опубликовано в: :J Invest Dermatol
Главные авторы: Kleffel, Sonja, Lee, Nayoung, Lezcano, Cecilia, Wilson, Brian J., Sobolewski, Kristine, Saab, Karim R., Mueller, Hansgeorg, Zhan, Qian, Posch, Christian, Elco, Christopher P., DoRosario, Andrew, Garcia, Sarah S., Thakuria, Manisha, Wang, Yaoyu E., Wang, Linda C., Murphy, George F., Frank, Markus H., Schatton, Tobias
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821468/
https://ncbi.nlm.nih.gov/pubmed/26827764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2015.12.038
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