Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.

Expression cDNA cloning and structural analysis of the human keratinocyte growth factor receptor (KGFR) revealed identity with one of the fibroblast growth factor (FGF) receptors encoded by the bek gene (FGFR-2), except for a divergent stretch of 49 amino acids in their extracellular domains. Bindin...

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Autores principales: Miki, T, Bottaro, D P, Fleming, T P, Smith, C L, Burgess, W H, Chan, A M, Aaronson, S A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC48213/
https://ncbi.nlm.nih.gov/pubmed/1309608
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