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Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope
Cyclin-dependent kinases (CDKs) play key roles in cell cycle regulation. Genetic analysis in mice has revealed an essential role for Cdk2 in meiosis, which renders Cdk2 knockout (KO) mice sterile. Here we show that mice deficient in RingoA, an atypical activator of Cdk1 and Cdk2 that has no amino ac...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820962/ https://ncbi.nlm.nih.gov/pubmed/27025256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11084 |
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