Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner

BACKGROUND: Males and females have a different predisposition for the development of intestinal disorders, like inflammatory bowel disease (IBD). We hypothesized that sex specific differences in intestinal immune responses may underlie this bias. To test this hypothesis, we studied sex differences i...

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Udgivet i:Biol Sex Differ
Main Authors: Elderman, Marlies, van Beek, Adriaan, Brandsma, Eelke, de Haan, Bart, Savelkoul, Huub, de Vos, Paul, Faas, Marijke
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820953/
https://ncbi.nlm.nih.gov/pubmed/27051505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-016-0075-9
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