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Sequence features accurately predict genome-wide MeCP2 binding in vivo
Methyl-CpG binding protein 2 (MeCP2) is critical for proper brain development and expressed at near-histone levels in neurons, but the mechanism of its genomic localization remains poorly understood. Using high-resolution MeCP2-binding data, we show that DNA sequence features alone can predict bindi...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820824/ https://ncbi.nlm.nih.gov/pubmed/27008915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11025 |
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