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NMRmix: A Tool for the Optimization of Compound Mixtures in 1D (1)H NMR Ligand Affinity Screens

[Image: see text] NMR ligand affinity screening is a powerful technique that is routinely used in drug discovery or functional genomics to directly detect protein–ligand binding events. Binding events can be identified by monitoring differences in the 1D (1)H NMR spectrum of a compound with and with...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Stark, Jaime L., Eghbalnia, Hamid R., Lee, Woonghee, Westler, William M., Markley, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820789/
https://ncbi.nlm.nih.gov/pubmed/26965640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00121
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