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Structural basis for the membrane association of ankyrinG via palmitoylation

By clustering various ion channels and transporters, ankyrin-G (AnkG) configures the membrane-excitation platforms in neurons and cardiomyocytes. AnkG itself localizes to specific areas on the plasma membrane via s-palmitoylation of Cys. However, the structural mechanism by which AnkG anchors to the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Fujiwara, Yuichiro, Kondo, Hiroko X., Shirota, Matsuyuki, Kobayashi, Megumi, Takeshita, Kohei, Nakagawa, Atsushi, Okamura, Yasushi, Kinoshita, Kengo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820748/
https://ncbi.nlm.nih.gov/pubmed/27046665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23981
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