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Mechanistic Insights into the Role of C-Type Lectin Receptor/CARD9 Signaling in Human Antifungal Immunity

Human CARD9 deficiency is an autosomal recessive primary immunodeficiency disorder caused by biallelic mutations in the gene CARD9, which encodes a signaling protein that is found downstream of many C-type lectin receptors (CLRs). CLRs encompass a large family of innate recognition receptors, expres...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Drummond, Rebecca A., Lionakis, Michail S.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820464/
https://ncbi.nlm.nih.gov/pubmed/27092298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2016.00039
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