A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti–hepatitis C target

G-quadruplex (G4) is one of the most important secondary structures in nucleic acids. Until recently, G4 RNAs have not been reported in any ribovirus, such as the hepatitis C virus. Our bioinformatics analysis reveals highly conserved guanine-rich consensus sequences within the core gene of hepatiti...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Wang, Shao-Ru, Min, Yuan-Qin, Wang, Jia-Qi, Liu, Chao-Xing, Fu, Bo-Shi, Wu, Fan, Wu, Ling-Yu, Qiao, Zhi-Xian, Song, Yan-Yan, Xu, Guo-Hua, Wu, Zhi-Guo, Huang, Gai, Peng, Nan-Fang, Huang, Rong, Mao, Wu-Xiang, Peng, Shuang, Chen, Yu-Qi, Zhu, Ying, Tian, Tian, Zhang, Xiao-Lian, Zhou, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820367/
https://ncbi.nlm.nih.gov/pubmed/27051880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501535
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