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Heterotrophic Production of Omega-3 Long-Chain Polyunsaturated Fatty Acids by Trophically Converted Marine Diatom Phaeodactylum tricornutum

We have created via metabolic engineering a heterotrophic strain of Phaeodactylum tricornutum that accumulates enhanced levels of the high value omega-3 long chain polyunsaturated fatty acid (LC-PUFAs) docosahexaenoic acid (DHA). This was achieved by generation of transgenic strains in which the Δ5-...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Hamilton, Mary L., Powers, Stephen, Napier, Johnathan A., Sayanova, Olga
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820307/
https://ncbi.nlm.nih.gov/pubmed/27005636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14030053
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