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Cellular Growth Arrest and Persistence from Enzyme Saturation

Metabolic efficiency depends on the balance between supply and demand of metabolites, which is sensitive to environmental and physiological fluctuations, or noise, causing shortages or surpluses in the metabolic pipeline. How cells can reliably optimize biomass production in the presence of metaboli...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Ray, J. Christian J., Wickersheim, Michelle L., Jalihal, Ameya P., Adeshina, Yusuf O., Cooper, Tim F., Balázsi, Gábor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820279/
https://ncbi.nlm.nih.gov/pubmed/27010473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004825
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