Effect of intellectual enrichment on AD biomarker trajectories: Longitudinal imaging study

OBJECTIVE: To investigate the effect of age, sex, APOE4 genotype, and lifestyle enrichment (education/occupation, midlife cognitive activity, and midlife physical activity) on Alzheimer disease (AD) biomarker trajectories using longitudinal imaging data (brain β-amyloid load via Pittsburgh compound...

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Publicado en:Neurology
Autores principales: Vemuri, Prashanthi, Lesnick, Timothy G., Przybelski, Scott A., Knopman, David S., Machulda, Mary, Lowe, Val J., Mielke, Michelle M., Roberts, Rosebud O., Gunter, Jeffrey L., Senjem, Matthew L., Geda, Yonas E., Rocca, Walter A., Petersen, Ronald C., Jack, Clifford R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820132/
https://ncbi.nlm.nih.gov/pubmed/26911640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002490
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