Stage-dependent loss of cortical gyrification as Parkinson disease “unfolds”

OBJECTIVE: Nigrostriatal terminal losses are known to progress most rapidly in early-stage Parkinson disease (PD) and then plateau, whereas cortical pathology continues and may provide a better marker of PD progression in later stages. We investigated cortical gyrification indices in patients with d...

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Veröffentlicht in:Neurology
Hauptverfasser: Sterling, Nicholas W., Wang, Ming, Zhang, Lijun, Lee, Eun-Young, Du, Guangwei, Lewis, Mechelle M., Styner, Martin, Huang, Xuemei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820131/
https://ncbi.nlm.nih.gov/pubmed/26888982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002492
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