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Building a Robust Tumor Profiling Program: Synergy between Next-Generation Sequencing and Targeted Single-Gene Testing

Next-generation sequencing (NGS) is a powerful platform for identifying cancer mutations. Routine clinical adoption of NGS requires optimized quality control metrics to ensure accurate results. To assess the robustness of our clinical NGS pipeline, we analyzed the results of 304 solid tumor and hema...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hiemenz, Matthew C., Kadauke, Stephan, Lieberman, David B., Roth, David B., Zhao, Jianhua, Watt, Christopher D., Daber, Robert D., Morrissette, Jennifer J. D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820127/
https://ncbi.nlm.nih.gov/pubmed/27043212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152851
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