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Proglucagon-Derived Peptides Do Not Significantly Affect Acute Exocrine Pancreas in Rats

OBJECTIVES: Reports have suggested a link between treatment with glucagon-like peptide 1 (GLP-1) analogues and an increased risk of pancreatitis. Oxyntomodulin, a dual agonist of both GLP-1 and glucagon receptors, is currently being investigated as a potential anti-obesity therapy, but little is kno...

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Détails bibliographiques
Publié dans:Pancreas
Auteurs principaux: Akalestou, Elina, Christakis, Ioannis, Solomou, Antonia M., Minnion, James S., Rutter, Guy A., Bloom, Stephen R.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820085/
https://ncbi.nlm.nih.gov/pubmed/26731187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000585
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