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Coupling of Replica Exchange Simulations to a non-Boltzmann structure reservoir

Computing converged ensemble properties remains challenging for large biomolecules. Replica exchange molecular dynamics (REMD) can significantly increase the efficiency of conformational sampling by using high temperatures to escape kinetic traps. Several groups, including ours, introduced the idea...

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Bibliografski detalji
Izdano u:J Phys Chem B
Glavni autori: Roitberg, Adrian E., Okur, Asim, Simmerling, Carlos
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819981/
https://ncbi.nlm.nih.gov/pubmed/17300191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp068335b
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