Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes

OBJECTIVE: Gout, caused by hyperuricaemia, is a multifactorial disease. Although genome-wide association studies (GWASs) of gout have been reported, they included self-reported gout cases in which clinical information was insufficient. Therefore, the relationship between genetic variation and clinic...

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Pubblicato in:Ann Rheum Dis
Autori principali: Matsuo, Hirotaka, Yamamoto, Ken, Nakaoka, Hirofumi, Nakayama, Akiyoshi, Sakiyama, Masayuki, Chiba, Toshinori, Takahashi, Atsushi, Nakamura, Takahiro, Nakashima, Hiroshi, Takada, Yuzo, Danjoh, Inaho, Shimizu, Seiko, Abe, Junko, Kawamura, Yusuke, Terashige, Sho, Ogata, Hiraku, Tatsukawa, Seishiro, Yin, Guang, Okada, Rieko, Morita, Emi, Naito, Mariko, Tokumasu, Atsumi, Onoue, Hiroyuki, Iwaya, Keiichi, Ito, Toshimitsu, Takada, Tappei, Inoue, Katsuhisa, Kato, Yukio, Nakamura, Yukio, Sakurai, Yutaka, Suzuki, Hiroshi, Kanai, Yoshikatsu, Hosoya, Tatsuo, Hamajima, Nobuyuki, Inoue, Ituro, Kubo, Michiaki, Ichida, Kimiyoshi, Ooyama, Hiroshi, Shimizu, Toru, Shinomiya, Nariyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2016
Soggetti:
Clinical and Epidemiological Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819613/
https://ncbi.nlm.nih.gov/pubmed/25646370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-206191
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