Cargando...
Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration
A zebrafish genetic screen for determinants of susceptibility to Mycobacterium marinum identified a hypersusceptible mutant deficient in lysosomal cysteine cathepsins that manifests hallmarks of human lysosomal storage diseases. Under homeostatic conditions, mutant macrophages accumulate undigested...
Gardado en:
| Publicado en: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cell Press
2016
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819607/ https://ncbi.nlm.nih.gov/pubmed/27015311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.034 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|