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In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction
[Image: see text] UDP-galactopyranose mutase (UGM) plays an essential role in galactofuranose biosynthesis in pathogens by catalyzing the conversion of UDP-galactopyranose to UDP-galactofuranose. Here we report the first crystal structure of a covalent intermediate in the UGM reaction. The 2.3 Å res...
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| Udgivet i: | Biochemistry |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American
Chemical Society
2016
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819441/ https://ncbi.nlm.nih.gov/pubmed/26836146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00035 |
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