Rescuing axons from degeneration does not affect retinal ganglion cell death

After a traumatic injury to the central nervous system, the distal stumps of axons undergo Wallerian degeneration (WD), an event that comprises cytoskeleton and myelin breakdown, astrocytic gliosis, and overexpression of proteins that inhibit axonal regrowth. By contrast, injured neuronal cell bodie...

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Bibliographic Details
Published in:Braz J Med Biol Res
Main Authors: de Lima, S., Mietto, B.S., Paula, C., Muniz, T., Martinez, A.M.B., Gardino, P.F.
Format: Artigo
Language:Inglês
Published: Associação Brasileira de Divulgação Científica 2016
Subjects:
Clinical Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819409/
https://ncbi.nlm.nih.gov/pubmed/27007653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20155106
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