Longitudinal Effects of Ketamine on Dendritic Architecture In Vivo in the Mouse Medial Frontal Cortex123

A single subanesthetic dose of ketamine, an NMDA receptor antagonist, leads to fast-acting antidepressant effects. In rodent models, systemic ketamine is associated with higher dendritic spine density in the prefrontal cortex, reflecting structural remodeling that may underlie the behavioral changes...

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Publicat a:eNeuro
Autors principals: Phoumthipphavong, Victoria, Barthas, Florent, Hassett, Samantha, Kwan, Alex C.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
Matèries:
New Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819286/
https://ncbi.nlm.nih.gov/pubmed/27066532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0133-15.2016
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