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What can we learn about lipoprotein metabolism and coronary heart disease from studying rare variants?
PURPOSE OF REVIEW: Rare variant association studies (RVAS) target the class of genetic variation with frequencies less than 1%. Recently, investigators have used exome sequencing in RVAS to identify rare alleles responsible for Mendelian diseases but have experienced greater difficulty discovering s...
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| Publicado no: | Curr Opin Lipidol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819247/ https://ncbi.nlm.nih.gov/pubmed/26844526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOL.0000000000000277 |
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