Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders

The smooth muscle cell directly drives the contraction of the vascular wall and hence regulates the size of the blood vessel lumen. We review here the current understanding of the molecular mechanisms by which agonists, therapeutics, and diseases regulate contractility of the vascular smooth muscle...

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Bibliographic Details
Published in:Pharmacol Rev
Main Authors: Brozovich, F.V., Nicholson, C.J., Degen, C.V., Gao, Yuan Z., Aggarwal, M., Morgan, K.G.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2016
Subjects:
Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819215/
https://ncbi.nlm.nih.gov/pubmed/27037223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.115.010652
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