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Glucocorticoids impair oocyte developmental potential by triggering apoptosis of ovarian cells via activating the Fas system

Previous studies indicate that stress damages oocytes with increased secretion of glucorticoids. However, although injection of female mice with cortisol decreased oocyte competence, exposure of mouse oocytes directly to physiological or stress-induced concentrations of glucorticoids did not affect...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yuan, Hong-Jie, Han, Xiao, He, Nan, Wang, Guo-Liang, Gong, Shuai, Lin, Juan, Gao, Min, Tan, Jing-He
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819190/
https://ncbi.nlm.nih.gov/pubmed/27040909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24036
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